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| Watanabe, Ken-ichi; Chambers, James K.; Uchida, Kazuyuki; Nibe, Kazumi; Ushio, Nanako; Horiuchi, Noriyuki; Kobayashi, Yoshiyasu; Nakayama, Hiroyuki. |
| The atypical cutaneous tumor of a 9-year-old mixed breed female dog was examined. The tumor was well-demarcated and histologically composed of a trichoblastic area, tricholemmal area and apocrine glandular area. Neoplastic cells in trichoblastic area and tricholemmal area had PAS-positive granules in the cytoplasm and were positive for pan-cytokeratin, cytokeratin 5/6, 14 and 19 and p63. Neoplastic cells in trichoblastic area were also positive for cytokeratin 15 and CD34. Neoplastic cells in apocrine glandular area were positive for pan-cytokeratin and cytokeratin 7,18 and 19. Myoepithelial cell proliferation with osteocartilaginous metaplasia was observed in this area. Since neoplastic cells showed multiphenotypic differentiation for hair follicles and... |
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Palavras-chave: Cutaneous mixed tumor; Dog; Hair follicle; Multiphenotypic differentiation. |
| Ano: 2017 |
URL: http://ir.obihiro.ac.jp/dspace/handle/10322/4453 |
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| Kato, Kentaro; Murata, Yuho; Horiuchi, Noriyuki; Inomata, Atsuko; Terkawi, Mohamad Alaa; Ishiwa, Akiko; Ogawa, Yohsuke; Fukumoto, Shinya; Matsuhisa, Fumikazu; Koyama, Kenji. |
| Background: Toxoplasma gondii is a highly prevalent protozoan that can infect all warm-blooded animals, including humans. Its definitive hosts are Felidae and its intermediate hosts include various other mammals and birds, including pigs. It is found in the meat of livestock which is a major source of human infection. Hence the control of toxoplasmosis in pigs is important for public health. We previously showed that dextran sulfate (DS), especially DS10 (dextran sulfate MW 10 kDa), is effective against T. gondii infection both in vitro and in mice. In this study, we asked whether DS affects T. gondii infection of pigs, one of the main animal sources of toxoplasmosis transmission to humans. Methods: Fourteen-day-old male pigs (n = 10) were infected with T.... |
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Palavras-chave: Dextran sulfate; Intermediate host; Pig; Public health; Toxoplasma gondii. |
| Ano: 2016 |
URL: http://ir.obihiro.ac.jp/dspace/handle/10322/4446 |
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| Tagawa, Michihito; Kurashima, Chihiro; Shimbo, Genya; Omura, Hiroshi; Koyama, Kenji; Horiuchi, Noriyuki; Kobayashi, Yoshiyasu; Kawamoto, Keiko; Miyahara, Kazuro. |
| A three-year-old spayed domestic short-haired cat presented for evaluation of weight loss, cardiomegaly and pleural effusion. Echocardiographic examination demonstrated a thickened pericardium with mild pericardial effusion and a large volume of pleural effusion characterized by exudate. Although the cat was treated with antibiotics, the clinical symptoms did not improve. The cat developed dyspnea and died on day 7. Necropsy revealed a large amount of modified transudates ascites, pleural effusion and markedly dilated pericardium. Histopathological examination revealed severe exudation of fibrin and granulation tissue in a thick layer of the epicardium. The cat was diagnosed with fibrinous pericarditis secondary to bacterial infection. |
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Palavras-chave: Cardiomegaly; Cat; Fibrinous pericarditis; Moraxella osloensis. |
| Ano: 2017 |
URL: http://ir.obihiro.ac.jp/dspace/handle/10322/4518 |
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| Suzuki, Haruka; Watanabe, Ken-ichi; Horiuchi, Noriyuki; Kobayashi, Yoshiyasu; Inokuma, Hisashi. |
| A 58-month-old Holstein cow showed anorexia, edema of the lower jaw and dewlap, jugular venous engorgement, abdominal gas, and watery diarrhea. Heart sounds were faint on auscultation, and decreased rumen motility was noted in physical examination. Echocardiography findings included adhesion of fibrin-like structures to the pericardium, highly echogenic periaortic region, and pericardial effusion, which suggested traumatic pericarditis or tumor formation. Although atypical mesothelial cells were observed in bloody pericardial fluid, no diagnosis was made. At complete necropsy, milky mass formation was observed on the epicardium. Histopathological examination led to a diagnosis of primary malignant pericardial mesothelioma. © 2017, Hokkaido University. All... |
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Palavras-chave: Congestive heart failure; Holstein; Pericardial mesothelioma. |
| Ano: 2017 |
URL: http://ir.obihiro.ac.jp/dspace/handle/10322/4561 |
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| Inokuma, Hisashi; Horiuchi, Noriyuki; Watanabe, Ken-ichi; Kobayashi, Yoshiyasu. |
| This retrospective study was conducted to clarify the clinical findings of an autosomal recessive cholesterol deficiency disorder in Holstein calves. Thirty-three calves with poor growth by uncertain causes from 2007 to 2016 comprised the study population of calves that were homozygous (n = 12) and non-homozygous (n = 21) for the disease. No significant group-dependent differences were found in the proportion with diarrhea or fever. Fewer calves with ataxia and anorexia were found in homozygotes. All affected calves showed muscular atrophy. Median RBC, Hb, and Ht values in affected calves were significantly lower. Median total cholesterol (TC) in homozygotes was extremely low, at 6.5 mg/dl (range, 5.0-15.0). TC readings under 10 mg/dl were thought to be... |
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Palavras-chave: Autosomal recessive cholesterol deficiency; Holstein; Retrospective study. |
| Ano: 2017 |
URL: http://ir.obihiro.ac.jp/dspace/handle/10322/4439 |
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